Appearance: pale yellow crystalline solid
Ammonium pyrrolidinedithiocarbamate 5108-96-3 is a potent inhibitor of NF κB (Nuclear Factor κB). Experiments show that micromolar amounts of this compound suppress IL-1β and completely inhibit the increase of nitric oxide synthase mRNA in response to IL-1β. Further studies suggest that PDTC ammonium salt also displays metal-ion chelating and antioxidant characteristics.
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