Appearance: white crystalline powder
Specific rotation[a]D20: +24.5~+25.5°(C=1,DMF)
Melting point: 153-155℃
Fmoc-D-leucine; Fmoc-D-Leu-OH 114360-54-2 is a Fmoc-protected leucine derivative. It is the standard lysine derivative for incorporating D-lysine residues into peptides. The sidechain Boc group of Fmoc-D-Lys(Boc)-OH is removed under acidic conditions such as when the peptide is cleaved from Wang resin or Rink amide resin. Fmoc-D-Lys(Boc)-OH may be especially useful in preparing new antimicrobial peptides with improved pharmaceutical characteristics. D-Lysine substituted into selected positions of some antimicrobial peptides can enhance antimicrobial activity
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