Appearance: White crystalline solid
Phenformin hydrochloride 834-28-6 is a hydrochloride salt of the biguanidine drug phenformin that displays anti-diabetic activity. It has been shown to increase AMPK activity without increasing AMP/ATP activity. It has been shown, however, that treating hearts with phenformin hydrochloride and then perfusing with Krebs-Henseleit buffer increases AMPK and AMP activity and also elevates phosphorylated acetyl-CoA carboxylase.
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