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Structure

Salsalate 552-94-3

Salsalate 552-94-3

Specifications

  • Catalogue No.: 33863
  • Product Name: Salsalate
  • Synonyms: 2-(2-Hydroxybenzoyl)oxybenzoic acid; salicyloxysalicylic acid
  • CAS: 552-94-3
  • EC: 209-027-4
  • MDL: MFCD00020252
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  • Price: $1000/5kg
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Properties

Assay: 98~102%
Appearance: white crystalline powder
Mp: 148-149 ℃
Standard: USP

Salsalate 552-94-3 is used to study the effect on palmitate-induced insulin resistance and hepatic steatosis in obese rats. Salsalate is a nonsteroidal anti-inflammatory drug (NSAID), a nonacetylated salicylate with no more problems of gastrointestinal bleeding than placebo. It inhibits synthesis and release of prostaglandins through the inactivation of cyclooxygenase-1 (COX-1) and COX-2. Salsalate is currently being investigated as a treatment for Type 2 diabetes with possible use to prevent the disease in people at risk. It reduces blood glucose concentrations in patients with type 2 diabetes, as well as in insulin-resistant patients without diabetes.

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